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DTSTART:20131103T020000
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UID:calendar.7176.field_date.0@calendar.lafayette.edu
DTSTAMP:20260615T112132Z
DESCRIPTION:Recent advances in DNA self-assembly have resulted in nanoscale
  graphs: \ncubes\, octahedrons\, truncated octahedra\, and even buckyballs
 \, as well as \nultra-fine meshes. These constructs serve emergent applica
 tions in \nbiomolecular computing\, nanoelectronics\, biosensors\, drug de
 livery systems\, \nand organic synthesis.\nOne construction method uses k-
 armed branched junction molecules\, called \ntiles\, whose arms are double
  strands of DNA with one strand extending beyond \nthe other\, forming a ‘
 sticky end’ at the end of the arm that can bond to \nany other sticky end 
 with complementary Watson-Crick bases. Another \nconstruction method\, cal
 led DNA origami\, ‘threads’ a single strand of DNA \nthrough the target st
 ructure and then uses short ‘staple’ strands to fold \nthe DNA into the de
 sired geometric shape.  A third method uses circular \nsingle strands of D
 NA to trace the faces of a structure.\nOften the underlying structure is a
  graph\, and in this case we use graph \ntheory to determine optimal desig
 n strategies for chemists and biologists \nproducing these nanostructures.
 \nThis is joint work with Greta Pangborn\, with undergraduate research \np
 articipation.
DTSTART;TZID=America/New_York:20130315T120000
DTEND;TZID=America/New_York:20130315T130000
LAST-MODIFIED:20130305T163327Z
LOCATION:Pardee 217
SUMMARY:'Graph Theory & DNA Self-Assembly'
URL;TYPE=URI:https://calendar.lafayette.edu/node/7176
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